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Obtaining enough synthetic mRNA for clinical use has long been a hurdle in treating conditions like cancer and infectious diseases.. Current mRNA production methods involve complex purification steps and chemicals, limiting large-scale manufacturing.

Biolayer Interferometry (BLI) technology has greatly advanced the process of antibody discovery, and the latest platforms offer reliable, high precision analysis which researchers can rely on.

This poster highlights several methods by which the downstream purification of viral vectors can be improved using chromatography methods to analyse and purify multiple AAV serotypes.

Recent advancements in affinity technology now support more robust and efficient Protein A chromatography. Hence, the latest Protein A solutions can enhance productivity, yield and accelerate products to market.

Affinity purification platforms such as Protein A or L are well-established in the manufacturing process of therapeutic monoclonal antibodies. However, with the development of engineered modalities such as bi-specific antibodies, fragments and Fc-fusion proteins, challenges in the downstream process of these molecules arise.

Increased demand has led to an overwhelming volume of LC-MS/MS data and a requirement for analytical software that can simplify its interpretation. This poster highlights a new, comprehensive software solution capable of eliminating the otherwise overwhelming efforts of manual data interpretation.

Drug discovery is a time-consuming, resource-intensive part of developing therapeutic targets. This is especially true for commonly considered 'undruggable' targets such as transmembrane proteins.

Whether you are working in cell line development, 3D biology, drug screening —or a combination of the three — technologies that maximize throughput and reproducibility can free up your time and give you greater insights.

The growing use of RNA-based vaccines and therapies has focused much attention and effort on developing conditions for maximizing the yield and efficiency of the in vitro transcription (IVT) reactions used to produce mRNA. IVT procedures involve the biosynthesis of RNA from a linear DNA template containing an appropriate transcription promoter. But how do different buffer conditions and nucleotide concentrations impact the IVT reaction?

Nucleic acid amplification and detection techniques are highly valuable tools that can be used across a wide range of applications... Real-time PCR, also known as quantitative PCR (qPCR), is the gold-standard for sensitive, specific detection and quantification of nucleic acid targets.