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A gold strand of DNA.
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Gene Therapy Success in Hereditary Angioedema Patients

A single dose of a CRISPR/Cas9 therapy has been successful in treating hereditary angioedema, reports an initial study of ten patients.
Virus particles.
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Novel Vaccines Use DNA Particles That Mimic Viruses

Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
A 3D rendering of intestines.
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Promising Stem Cell-Based Crohn’s Disease Therapy Developed

A stem cell therapy for Crohn's disease based on marrow-derived mesenchymal stem cells (hMSCs) helped heal the lining of the intestines and prompted a positive immunologic response.
A child in bed unwell.
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Bacterial Meningitis Causes Lifelong Effects in One-Third of Children

A new study by researchers at the Karolinska Institute, published in JAMA Network Open, sheds some light on the long-term effects of bacterial meningitis.
Cancer cells.
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Secondary Cancers Are Rare Following CAR T-Cell Therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine.
An illustration of editing of a DNA double helix.
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Gene Therapy Restores Hearing in Small Trial for Kids With Hereditary Deafness

Five out of six children with a type of hereditary hearing loss have shown improvement in their hearing and speech recognition after treatment with an experimental gene therapy. This is the first gene therapy trial for children with this type of hearing loss.
Vaccine vials.
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Single Typhoid Vaccine Dose Has Lasting Efficacy in Children

A single dose of the typhoid conjugate vaccine, Typbar TCV®, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study.
Cancer cells.
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mRNA Therapeutic Effective Against Ovarian Cancer in Mice

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study offers hope that this could change in the medium term.
Cell therapy.
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CAR T Cells Slow Aging in Mice by Attacking Senescent Cells

Senescent cells accumulate as we age. CAR T cells can be programmed to seek them out and destroy them. The image above shows healthy pancreatic tissue samples from an old mouse treated with CAR T cells as a young pup.
A person receiving a vaccine shot in their arm.
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No Cervical Cancer Cases Following HPV Vaccination in Scotland

No cervical cancer cases have been observed in women who received the human papillomavirus (HPV) vaccine at age 12 or 13 in Scotland since the program began in 2008, according to a new study.
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