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Gene Therapy Success in Hereditary Angioedema Patients
A single dose of a CRISPR/Cas9 therapy has been successful in treating hereditary angioedema, reports an initial study of ten patients.
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Novel Vaccines Use DNA Particles That Mimic Viruses
Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
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Promising Stem Cell-Based Crohn’s Disease Therapy Developed
A stem cell therapy for Crohn's disease based on marrow-derived mesenchymal stem cells (hMSCs) helped heal the lining of the intestines and prompted a positive immunologic response.
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Bacterial Meningitis Causes Lifelong Effects in One-Third of Children
A new study by researchers at the Karolinska Institute, published in JAMA Network Open, sheds some light on the long-term effects of bacterial meningitis.
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Secondary Cancers Are Rare Following CAR T-Cell Therapy
The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine.
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Gene Therapy Restores Hearing in Small Trial for Kids With Hereditary Deafness
Five out of six children with a type of hereditary hearing loss have shown improvement in their hearing and speech recognition after treatment with an experimental gene therapy. This is the first gene therapy trial for children with this type of hearing loss.
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Single Typhoid Vaccine Dose Has Lasting Efficacy in Children
A single dose of the typhoid conjugate vaccine, Typbar TCV®, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study.
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mRNA Therapeutic Effective Against Ovarian Cancer in Mice
Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study offers hope that this could change in the medium term.
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CAR T Cells Slow Aging in Mice by Attacking Senescent Cells
Senescent cells accumulate as we age. CAR T cells can be programmed to seek them out and destroy them. The image above shows healthy pancreatic tissue samples from an old mouse treated with CAR T cells as a young pup.
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No Cervical Cancer Cases Following HPV Vaccination in Scotland
No cervical cancer cases have been observed in women who received the human papillomavirus (HPV) vaccine at age 12 or 13 in Scotland since the program began in 2008, according to a new study.
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