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Vaccine Lowers Cholesterol Levels in Preclinical Trials

A newly developed vaccine could offer an inexpensive way to lower "bad" cholesterol, improving heart health.
A syringe and a vaccine vial on a blue background.
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Nanoparticle-Based Flu Vaccine Shows Promise in Early Tests

A new nanoparticle-based vaccine could provide broad, rather than seasonal, protection against influenza A.
A child receives an injection from a clinician.
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Most US Parents Plan To Vaccinate Their Children Against the “Tripledemic”

The first national study of its kind suggests that most US parents plan to vaccinate their children against influenza, COVID-19 and respiratory syncytial virus.
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Study May Enable Effective Vaccination Plans During Pregnancy

Researchers have developed the first computer-based predictive model of maternal vaccination and placental antibody transfer.
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Epilepsy Gene Therapy Reduces Seizures in Mouse Study

Researchers have developed a new gene therapy to cure a devastating form of childhood epilepsy, which has been shown to reduce seizures in mice.
Colorized 3D prints of HIV virus particles.
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Greater CD8+ T-Cell Activity May Increase HIV Immunity

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID).
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Potential Vaccine Developed Against Antibiotic-Resistant Enterococci

Membrane vesicles released by bacteria could be candidates for new vaccines against antibiotic-resistant enterococci bacteria that can be released naturally in the body.
Double helix structure of DNA.
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Just a One Letter Difference in DNA Affects the Activation of the Immune System

One-letter difference in our DNA determines whether BCG vaccine provides good protection against tuberculosis or not. Researchers have elucidated how that one letter difference affects the activation and deactivation of the immune system.
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Cell Therapy Improves Quality of Life in Advanced Heart Failure Trial

Stem cell-based therapy improved quality of life for patients with advanced heart failure, Mayo Clinic researchers and international collaborators discovered in a late-stage multinational clinical trial.
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New Cell Therapy Approach Shows Early Promise in Small Trial

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial.
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