Latest Posters
Poster
Choosing the Right Parameters for Your UV-Vis Measurement
The Agilent Optimum Parameters Poster is a handy wall chart that provides information about choosing solvents, cuvette types, and managing your instrument parameters.
Poster
MALDI Imaging Mass Spectrometry for the Study of Cardiovascular Pathology
Download this poster to learn how a comprehensive MALDI mass spectrometry (MALDI-IMS) approach to formalin-fixed paraffin-embedded (FFPE) tissue samples was developed to study cardiovascular pathology.
Poster
Young Adult Women’s Relationship Status and HPV Risk Perceptions: A Barrier to HPV Vaccination?
Human papillomavirus (HPV) vaccine rates continue to be low in the United States. Young women ages 18-26 years are eligible for catch-up vaccination but previous research shows that relationships status and percieved risk may be barriers to HPV vaccination. The purpose of this quantitative study was to assess the association between relationship status and perceived risk for HPV among young adult women.
Poster
Histone Deacetylase 6 (HDAC6) As A Therapeutic Target in Chronic Lymphocytic Leukemia
This study investigates the role of histone deacetylase 6 (HDAC6) in chronic lymphocytic leukemia and establishes it as a novel therapeutic target for the treatment of this disease.
Poster
Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and Invasion
In summary, ISG15 expression levels are crucial for trophoblast morphology and function (migration/invasion). By blocking trophoblast invasion, reduced ISG15 levels could contribute to impaired spiral artery transformation that reduces utero-placental blood flow in preeclampsia. Thus, agents inducing ISG15 expression are likely to be therapeutic in preeclampsia.
Poster
Improved T Cell Activation Bioassays for Development of Bispecific Antibodies and Engineered T Cell Immunotherapies
Here we describe a platform of T cell activation bioassays for the development of CD3 bispecific antibodies and engineered T cell immunotherapies.
Poster
Quantitative Cell-based Bioassays for Individual or Combination Immune Checkpoint Immunotherapy
Cell-based reporter bioassays overcome the limitations of primary cell-based assays for functional characterization of antibody and other biologics drugs, targeting individual or combination immune checkpoint receptors. Here we show a portfolio of immune inhibitory checkpoint bioassays, that can be used for antibody screening, characterization, potency and stability studies.
Poster
Fc Effector Bioassays for Rapid and Quantitative Measurement of ADCC and ADCP Mechanisms of Action
Drug developers are rapidly adopting Fc effector function reporter-based bioassays to measure antibody Fc functions such as ADCC and ADCP activity during the development of therapeutic antibodies. Here we show application of a suite of FcgR Reporter Bioassays to elucidate and characterize antibody MOA.
Poster
Bioluminescent Kinase Profiling Systems for Characterizing Small Molecule Kinase Inhibitors
In order to profile compounds against a broad panel of kinases, in-house profiling requires rigorous kinase assay development.
Poster
Pyroptosis Detection via Multiplexing Cell Death and Bioluminescent Caspase-1 Activity Assessments
Researchers developed a convenient method to confirm pyroptosis. Inflammasome activation triggers rapid pyroptosis. Preventing pyroptosis may shift form of cell death
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