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Using Stem Cells To Enhance Cancer Immunotherapy Without Genetic Modification
A joint research team has used stem cells to generate human immune cells for application in cancer immunotherapy. This breakthrough platform is expected to significantly enhance cancer-targeting efficacy.
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Discovery Could Lead to “Double Blow” Against Cancers
A multinational team of researchers led by Columbia University has discovered that tumors can repurpose a single cellular protein to hide themselves from the immune system in two distinct ways.
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Computer Models May Predict Breast Cancer Patients’ Treatment Responses
Monash University-led research is using maths to predict how new combination therapies can help patients with breast cancer who no longer respond to conventional therapies.
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Blood Tests Could Predict Poor CAR T-Cell Therapy Outcomes
Blood tests could predict outcomes of CAR T-cell therapy, helping to optimize cancer treatments and improve their safety and efficacy.
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Single-Cell Analysis Explains Cancer Patients' Sensitivity to Epigenetic Drugs
Researchers described the effects of chemotherapy at the single cell resolution in the bone marrow of Myelodysplastic Syndrome patients. The results help better understand which cellular populations are more sensitive to an epigenetic drug.
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Novel Drug Targets Aggressive Breast Cancer
A promising drug could lead to a new treatment for the most aggressive form of breast cancer, which affects thousands of women each year. A pre-clinical study found the new drug successfully inhibits the growth of triple negative breast cancer.
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Moderate Levels of Radon Found To Hike Stroke Risk
Radon is the second leading cause of lung cancer. Now a new study has found exposure to this invisible, odorless gas is also linked to an increased risk of stroke.
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Immune Cells’ “Killer Instinct” Can Be Reawakened in Tumors
Some immune cells in our bodies see their "killer instinct" restricted after entering solid tumors, but it can be reawakened, reports a new study.
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Protein Linked to Pancreatic Cancer Metastasis Identified
Researchers from the University of California, Davis showed that abnormal expression of the protein Engrailed-1 (EN1) promotes pancreatic cancer progression and metastasis in vitro and in mouse models.
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Epigenetic Status Determines the Fate of Cancer Cells
Scientists investigated in mice how spreading tumor cells behave at the site of metastasis: Some tumor cells immediately start to form metastases. Others leave the blood vessel and may then enter a long period of dormancy.
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