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Combination Drug Kills Cancer Cells With Deadly Influx of Calcium
Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.
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Inherited Mutations May Predict Interval Breast Cancer
An investigation conducted by researchers at Karolinska Institutet has led to a discovery in breast cancer diagnostics and treatments that could reshape screening programs and clinical approaches.
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Secondary Cancers Are Rare Following CAR T-Cell Therapy
The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine.
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Circadian Clock Gene Has a Variable Role in Cancer
A Cancer Research study has found that the circadian clock – which synchronizes physiological and cellular activities with the day-night cycle and is generally thought to be tumor suppressive – in fact has a contextually variable role in cancer.
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Genetic Study Estimates Risk of Death From Prostate Cancer
Just by looking at a short portion of a man’s genome it is possible to estimate the probability that he will die from prostate cancer—even before he has the cancer—thanks to a massive genetic study by RIKEN researchers.
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Why Don’t Cancer Immunotherapies Work for Everyone?
A multi-institutional study co-authored by University of Texas at Arlington scientists uncovered a mechanism by which cancer cells prevent the immune system from activating and attacking the cancerous invaders.
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mRNA Therapeutic Effective Against Ovarian Cancer in Mice
Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study offers hope that this could change in the medium term.
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Breakthrough for Breast Cancer Bone Metastases
A promising new immunological pathway that could be used to treat breast cancer that has metastasized to bone has been identified.
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Novel Immunotherapy Targets Senescent Cells To Make Chemotherapy More Effective
Researchers from IRB Barcelona describe a mechanism by which senescent cells generated by chemotherapy survive inside tumours. A new immunotherapy in animal models eliminates these senescent cells and improves the effectiveness of chemotherapy.
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No Cervical Cancer Cases Following HPV Vaccination in Scotland
No cervical cancer cases have been observed in women who received the human papillomavirus (HPV) vaccine at age 12 or 13 in Scotland since the program began in 2008, according to a new study.
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