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Treating Genetic Epilepsy by Replacing "Lost" Enzyme

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.
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Immune Cell Enzyme Links the Body and Brain During Stress

A collaboration of scientists provide new evidence that a specific immune cell enzyme is increased in stressed mice, and in patients with major depressive disorder.
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When It Comes to Knee Pain, The Size of Your Meniscus Matters

With all of the fantastic imaging techniques available in healthcare today, clinicians are capable of diagnosing tissue and joint deformities using non-invasive imaging with remarkable accuracy.
Cells.
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Existing Drug May Aid Organ Donation, Study Suggests

Study suggests that a pain relief drug can quickly and reversibly induce a sleep-like state in cells and organs could facilitate organ transplantation and prevent irreversible tissue injury.
A plastic model of a pair of lungs.
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Cell Therapy Shows Promise for Severe Lung Condition in Small Trial

An initial trial suggests a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome resulting from Covid-19.
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Scientists Code ChatGPT To Design New Drug Compounds

Generative AI like ChatGPT can do more than help write emails — it can also design new drugs to treat disease, reports a new study that shows how AI can generate unique molecular structures as potential drugs.
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Breast Cancer Drug's Efficacy Can Be Restored After Resistance

Researchers have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can restore the effectiveness of the breast cancer drug T-DM1 if the cancer cells have developed resistance.
Neurons degrading.
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Potential Alzheimer’s Drug Discovered

A potential new drug to prevent Alzheimer’s disease in people with the so-called Alzheimer’s gene has been discovered by a University of Arkansas for Medical Sciences.
A bacteria, artificially colorized in purple.
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Bacteria’s “Self-Killing” Activity Can Be Harnessed Against Antibiotic Resistance

A natural mechanism used by bacteria to protect themselves from viral attacks – by self-destructing – could be used to fight bacterial infections and antibiotic resistance.
Image depicting personalized medicine.
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Discovery Could Lead to Immune-Personalised Medicine for Lupus

Researchers discovered that a large proportion of lupus patients have antibodies to a protein called “Sm”, which is tightly linked to worse disease outcomes.
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