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Screening Strategies in Drug Discovery

This page provides educational resources, events, news and products related to screening strategies in drug discovery. Content will cover aspects including fragment-, cell- and target-based screening, high-throughput screening, phenotypic screening and virtual screening.

Screening Strategies in Drug Discovery – Highlights

The chemical structure of a cyclic molecule.

Advances in Fragment-Based Drug Discovery

Over the past decade, fragment-based drug discovery has garnered increasing interest among drug discovery experts and has established itself as a key approach within the field – acting as an alternative starting point for the discovery of high-quality lead candidates. This article discusses the evolution of FBDD, highlights key drug discoveries, and explores the advantages and challenges of harnessing this approach

Screening Strategies Used in Drug Discovery

This article highlights some of the different screening strategies used during drug discovery. Key advances and challenges associated with the techniques are also discussed.

Fragment-Based Drug Discovery Enters the Mainstream

This article will discuss the principles of fragment-based drug discovery and will highlight some examples of recent successes in this area.

Phenotypic Versus Target-Based Screening for Drug Discovery

Target-based screening has been the method of choice in drug discovery for the past two decades, but phenotypic screening is having something of a renaissance. We look at the advantages and applications of both.

Fragment-Based Drug Discovery

In this infographic, we review the history of fragment-based drug discovery, discuss the underlying concepts and examine the process in more detail.

Screening Strategies in Drug Discovery – News and Features

Scientists Code ChatGPT To Design New Drug Compounds

Generative AI like ChatGPT can do more than help write emails — it can also design new drugs to treat disease, reports a new study that shows how AI can generate unique molecular structures as potential drugs.

Benchtop NMR Breaks New Ground

Explore how recent technical advances in the design and construction of NMR instrumentation have eliminated practical issues that faced scientists whose experiments would benefit from the power of the technique, but who needed the speed and convenience of analysis unachievable with traditional high-field instruments.

Bacterial Immune System Makes Them More Susceptible to Antibiotics

A research team has now shown how the immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.

3D Atherosclerosis Model Enables High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease.

Using AI To Accelerate Novel Drug Design

Researchers have developed a platform that combines automated experiments with AI to predict how chemicals will react with one another, which could accelerate the design process for new drugs.

New Material Gulps Down Hydrogen, Spits It Out To Protect Fusion Reactor Walls

University of Wisconsin–Madison engineers have used a spray coating technology to produce a new workhorse material that can withstand the harsh conditions inside a fusion reactor.

Screening Strategies in Drug Discovery – Multimedia

TMi10

Pan-cancer Assay-ready Organoid Drug Screening With Robust, Reproducible, and Clinically-relevant Output

istock image tmi10

Revolutionizing Drug Discovery With Genomic Screening

3DCell

Harness the Power of 3D Cell Model Imaging

Screening Strategies in Drug Discovery – Webinars and Online Events

mRNA

Optimizing mRNA Purification Conditions by Using a High-Throughput Screening Approach

A High-Throughput Virtual Screening Approach to Identifying Novel SARS-CoV-2 Inhibitors content piece image

A High-Throughput Virtual Screening Approach to Identifying Novel SARS-CoV-2 Inhibitors

High-Content Analysis With 3D Organoids and Spheroids content piece image

High-Content Analysis With 3D Organoids and Spheroids

Related Products

High-Throughput Screening Methods for Drug Discovery

High-Throughput Screening Methods for Drug Discovery

SomaScan® 11K Assay Services: Unparallelled Protein Content for High-Plex Protein Profiling and Biomarker Discovery

App Note / Case Study

Discover a MS System That Is Proven Rapid and Complete

Biacore™ 8 Series SPR Systems

App Note / Case Study

Easy Set-Up for Protein Crystallization Experiments

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