Multiomics

In this article, we will explore some of the recent advances in proteomics and their potential wider impact.

A research team from The Walter and Eliza Hall Institute has adopted a single-cell, multi-omics approach to explore this question, focusing particularly on T and B lymphocyte formation. They discovered a new stage in lymphocyte development, information which the researchers say could "enrich future studies of the immune system". We wanted to know more.

This article will present two multiomics vignettes. One involves the search for a deeper understanding of food allergies and a potential path forward for treatment. Another will describe the response to bariatric surgery, a growing need as obesity trends upward in many parts of the world.

Professor Ron Heeren recently embarked on a study to bring together the spatial molecular information that is provided by MALDI-MSI with the microproteomic characterization generated by LC-MS on the same tissue specimen, on a single instrument. Heeren and colleagues were successful in this feat. Their work is published in the journal Proteomics and forms the basis of this interview.