Assessing Kinetics in Drug Discovery

Listicle

Published: February 8, 2022

Andy Tay, PhD

Assessing Kinetics in Drug Discovery content piece image

One of the most important factors determining the success of drug discovery is in vivo drug kinetics. This refers to the binding dynamics of a drug to its target including association and dissociation time which affect drug residence time in the body. Drug kinetics are often deprioritized as companies focus more on optimizing target-binding affinity and selectivity. This is despite increasing evidence that kinetic parameters may have a stronger correlation to drug efficacy than affinity parameters.

Download this listicle to learn more about:

The importance of kinetics
Experimental techniques
Computational modeling tools

Meet the Author

Andy Tay, PhD

Andy Tay holds a PhD from the University of California, Los Angeles. He completed his postdoctoral training at Stanford University where he developed nanotechnologies for immuno-engineering. Andy Tay is currently a Presidential Young Professor at the National University of Singapore. His lab is dedicated to developing innovative approaches for cancer immunotherapy and tissue repair.