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Drug Discovery

Drug Discovery

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Advanced Cell Models

This page provides educational resources, events, news and products related to advanced cell models. Content will cover aspects from the creation of organoids and organs-on-chips, to how they are applied to solve research questions, discover and test therapeutics and improve health.

Advanced Cell Models – Highlights

Blue cells.

Cellular Insights: How Researchers Are Using Cell Models To Study the Mechanisms of Disease

This article will discuss how cell models are enabling researchers to elucidate the underlying biological mechanisms of disease to support diagnostic and therapeutic development.

Advances in Spheroid and Organoid Engineering and Applications

In this article, we look at some recent advances and applications and where the field of three-dimensional tissue culture is heading.

How Far Can Organs-on-Chips Go On Their Own?

Great hope has been placed on organ-on-chip models to provide a complex and predictive in vitro models that can recapitulate the human drug response. How far can they go? This article delves into whether organ-on-chips can live up to expectations, and in particular, whether they can do it alone.

How Organoids Are Fueling Infectious Disease Research and Personalized Medicine

In this article, we discuss organoids in the context of personalized medicine and infectious disease and explore how they provide a new window into disease and fuel the discovery of new therapeutics.

Microphysiological Systems

Microphysiological systems (MPS) are two- or three-dimensional cellular platforms that are designed to recapitulate the physiology and function of the human body in vitro.

Advanced Cell Models – News and Features

Existing Drug May Aid Organ Donation, Study Suggests

Study suggests that a pain relief drug can quickly and reversibly induce a sleep-like state in cells and organs could facilitate organ transplantation and prevent irreversible tissue injury.

Using Stem Cells To Enhance Cancer Immunotherapy Without Genetic Modification

A joint research team has used stem cells to generate human immune cells for application in cancer immunotherapy. This breakthrough platform is expected to significantly enhance cancer-targeting efficacy.

Protein Linked to Pancreatic Cancer Metastasis Identified

Researchers from the University of California, Davis showed that abnormal expression of the protein Engrailed-1 (EN1) promotes pancreatic cancer progression and metastasis in vitro and in mouse models.

Functional Human Brain Tissue 3D-Printed for First Time

The first 3D-printed brain tissue could change the way researchers investigate neurological disorders.

mRNA Therapeutic Effective Against Ovarian Cancer in Mice

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study offers hope that this could change in the medium term.

“Mini-Placentas” Shine Light on the Cause of Pre-Eclampsia

With the incidence of pre-eclampsia slowly creeping up, researchers from the University of Cambridge have developed a new way to study this condition as outlined in their paper published in Cell Stem Cell.

Advanced Cell Models – Multimedia

Organoid

Your Guide to Culturing Organoids

TMi10

Organoids in Industry: Disease Modeling Platforms to Accelerate Drug Discovery

TMi10

Pan-cancer Assay-ready Organoid Drug Screening With Robust, Reproducible, and Clinically-relevant Output

Advanced Cell Models – Webinars and Online Events

Methods and Reagents for Culturing and Characterizing Organoids and Cancer Spheroids

Methods and Reagents for Culturing and Characterizing Organoids and Cancer Spheroids

AMA:Body-On-A-Chip Promotional Image

Ask Me Anything: Body-on-a-Chip

How To Stain and Clear Large Samples for 3D Light Sheet Microscopy content piece image

How To Stain and Clear Large Samples for 3D Light Sheet Microscopy

Related Products

An organ-on-a-chip.

CN Bio and Altis Biosystems Partner To Develop Next-Generation Human Gut/Liver In Vitro Model

3D Organoid Research Solutions

CN Bio PhysioMimix Organ-on-a-Chip Data Supports Inipharm’s INI-822 for Metabolic Liver Disease Treatment

Cultrex™ BME Matrices: Mimic Your Cells Native Microenvironment

CellXpress.ai Automated Cell Culture System - The Future of Cell Culture Backed by Machine Learning and Data-Driven Science

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