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Continuous Flow Synthesis: Laboratory Approach & Protocol for Scale-up
Amol Kulkarni, National Chemical Laboratory, speaking at Flow Chemistry India.
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Exploring Protein-protein Interactions Using Scaffolded and Assembled Peptides as Synthetic Binding Site Mimics
Jutta Eichler, University of Erlangen-Nuremberg, speaking at Discovery Chemistry Congress 2015.
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Choosing & Using Fragments in the Generation of Selective Kinase Inhibitors
There is often a debate about just how useful fragments are for well-established conventional targets such as protein kinases. Fragment screening however can be extremely valuable, providing critical ideas that lead to novelty, demonstrating how to achieve selectivity, helping dissect and make the most of HTS and literature compounds, alongside maximising ligand efficiency.
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Bioorthogonal Palladium-Labile Prodrugs for Site-Specific Anticancer Therapy
Asier Unciti-Broceta, University of Edinburgh, speaking at Discovery Chemistry Congress 2015.
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Tumour Regression after Intravenous Administration of Novel Tumour-targeted Nanomedicines
In this talk, Christine Dufes demonstrates that the intravenous administration of a tumour-targeted dendriplex led to tumour disappearance of 90% of the tested tumours over one month.
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Magneto-plasmonic Nanoparticle Platform for Capture, Separation and Enumeration of Rare Cells
In this presentation we will explore the opportunities afforded by the hybrid magneto-plasmonic nanoparticles and PA imaging for the development of a low cost simple and nearly real-time assays for capture, separation and enumeration of rare cells.
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Regulation of antibody immunotherapy by fine-tuning FcR interactions
In this talk, Mark Cragg, presents evidence that different mAb's interact with Fc receptors differently in order to achieve their therapeutic activities.
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