Latest Posters
Poster
Complete alignment identification of CRISPR-Cas9 genomic off-targets using Edit-R CRISPR specificity tool and a comprehensive analysis of positional mismatch tolerance
A web tool that performs complete crRNA specificity checking is introduced. In addition, we evaluated positional off-targeting of the CRISPR system.
Poster
MicroRNAs as Bile-Based Biomarkers in Pancreatic Cancer and Biliary Tract Cancers
In this study, the role of miRNAs has been assessed in a large cohort of pancreatic cancer.
Poster
Is Oxford Nanopore Technology Ready for Clinical Diagnostics?
Our objective is to validate diagnostic services using Oxford Nanopore’s Minion in the first instance and to evaluate the cost and performance compared to existing sequencing technology in areas such as tumour DNA sequencing (and circulating tumour DNA), virology, microbiology, genetics and HLA-typing.
Poster
Determination of the Fat Content Profile of different Chocolate Products using an Automated Workflow for the Generation of Fatty Acid Methyl Esters (FAME)
The method allows for automated determination of total fat content and quantitative analysis of saturated and unsaturated cis- and trans- fatty acids of different chocolate products.
Poster
Performance of the D5000 and High Sensitivity D5000 ScreenTape Assays for the 4200 TapeStation System
Here, we focus on quantification, sizing, and sensitivity of both D5000 ScreenTape assays.
Poster
Designing highly functional and specific guide RNAs for knockout and achieving precise knockin using the homology-directed repair pathway
We aim to better understand the parameters affecting CRISPR-Cas9 editing efficiency for functional gene knockout utilized synthetic crRNAs and tracrRNA.
Poster
What Are You Eating? An Analysis of Dietary Intake Measures Among College Students
To better understand the dietary practices of emerging adults, and college students more specifically, it is necessary to use effective measurement techniques. The purpose of this critique is to compare dietary intake measures used in research assessing dietary practices among college students.
Poster
Genomic Analysis of L5178Y tk+/- Cells and their Induced tk-/- Mutant Colonies
The goal of this pilot study was to exploit NGS technology with a view to shedding new light on the genome of cells used in the MLA, as well as the changes induced as a result of the exposure to mutagens.
Poster
Applications of chemically modified synthetic guide RNA for CRISPR-Cas9 genome editing
Our results indicate that MS modifications are required for experiments with co-electroporation of Cas9 mRNA and synthetic gRNA, yet have no impact on editing efficiency when delivered with lipid-based transfection reagents.
Poster
Highly Accurate HCV Genotyping by Targeted Next Generation Sequencing
The recent fast advancement of next generation sequencing (NGS) technologies allowing for unprecedented speed and accuracy in analyzing viral genomes are opening new ways to further improve diagnostic genotyping of HCV.
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