Latest App Notes & Case Studies

Despite daily use in every life science laboratory, best pipetting practices are not as well-known as one might expect. Many users are self-taught and have never received formal pipetting training during their professional career.

Current in vitro models of the small intestine offer limited predictivity due to their reliance on immortalized cell lines and static culture. To better predict human response to drug candidates, researchers need a model than can more closely recreate the intestinal microenvironment.

Download this app note to discover how you can overcome challenges such as maintaining the shape and size of spheroids to reduce variability.

To successfully use these models across a variety of research disciplines and applications, approaches that reduce variability and technology pipelines to image and quantify these complex cell models are required.

Download this app note to discover a microplate reader that covers a broad range of cell viability assay readouts, provides high sensitivity and full flexibility and offers a fast and easy assay setup.

Discovery of novel immunotherapies that specifically target and enhance the T cell response against cancer is a rapidly expanding research area. Robust and relevant in vitro models for evaluation of these immunotherapies is essential throughout their development.

Variants of SARS-CoV-2 have been emerging and circulating around the world since the start of the COVID-19 pandemic. Recombinant proteins, particularly those corresponding to variants of spike (S) protein, are required to study transmissibility and immune escape.

COVID-19 is caused by the SARS-CoV-2 virus. While some patients have mild or asymptomatic illness, for others it can be fatal. Understanding the immune response to SARS-CoV-2 at a molecular level is useful for the development of effective vaccines, treatments and prognostic tests.

The University of Szeged is one of Hungary’s leading research institutions with a long history of pioneering scientific achievements. For generations, the university’s scholars have been focused on collecting and storing biological samples for educational purposes as well as for clinical, biomedical and physiological research.

The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However, out-of-focus fluorescence increases background, reduces contrast and makes accurate image segmentation more challenging.