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Latest Posters

Primary Human Hepatocytes 3D <i>in vitro</i> Culture Model for Studying Hepatic Function content piece image
Poster

Primary Human Hepatocytes 3D in vitro Culture Model for Studying Hepatic Function

Primary Human Hepatocyte (PHH) culture provides the closest in vitro model to human liver that can produce a metabolic profile of a given drug very similar to that found in vivo. Recently we have developed an easy-to-assemble user-friendly in vitro Primary Human Hepatocyte (PHH) 3D-spheroid model
5 Steps to Multiplexed Fluorescent Western Blotting content piece image
Poster

5 Steps to Multiplexed Fluorescent Western Blotting

Download this free poster for step-by-step advice on troubleshooting your western blotting for protein analysis.
3D Spheroid Culture Workflow using iPSC-induced Human Neurons content piece image
Poster

3D Spheroid Culture Workflow using iPSC-induced Human Neurons

To develop a neuronal 3D spheroid culture system, we tested iPSC-derived human motor neurons and cortical glutamatergic neurons using the S-BIO PrimeSurface Ultra Low Attachment Micoplates.
Spontaneous Calcium Oscillations of Networked Human iPSC Derived Cortical Neurons as a Sensitive Model for Neurotoxicity Screening content piece image
Poster

Spontaneous Calcium Oscillations of Networked Human iPSC Derived Cortical Neurons as a Sensitive Model for Neurotoxicity Screening

BrainXell's human neuron culture platforms provide a means to model the human brain in a dish and perform in vitro functional assays. This system enables the screening of disease phenotypes and pharmacological agents that alter neuronal activity.
Identification of New Hit Compounds Using a High-Throughput Phenotypic Screen with SMA Patient iPSC-Derived Motor Neurons content piece image
Poster

Identification of New Hit Compounds Using a High-Throughput Phenotypic Screen with SMA Patient iPSC-Derived Motor Neurons

Spinal muscular atrophy (SMA) is an inheritable cause of infant mortality that is characterized by the loss of lower motor neurons and skeletal muscle atrophy. The degeneration of motor neurons is caused by insufficient levels of survival motor neuron (SMN) protein, which is encoded by two nearly identical genes SMN1 and SMN2. Most cases of SMA harbour homozygous deletions of the SMN1 gene and retain at least one copy of SMN2.
Optimized Conditions for MEA Assay with Human iPSC-Derived Spinal Motor Neurons, Glutamatergic Neurons and Mixed Cortical Neurons content piece image
Poster

Optimized Conditions for MEA Assay with Human iPSC-Derived Spinal Motor Neurons, Glutamatergic Neurons and Mixed Cortical Neurons

In order to generate a robust protocol for MEA recording on hiPSC- derived neurons, we evaluated several conditions, which could affect culture performance (1.neuron seeding density; 2.seeding medium; 3.astrocyt eco-culture). These conditions were evaluated with BrainXell’s hiPSC-derived spinal motor neurons, cortical glutamatergic neurons and mixed cortical neurons.
ALS Drug Discovery via High-Throughput Phenotypic Screening Using iPSC-Derived Human Motor Neurons content piece image
Poster

ALS Drug Discovery via High-Throughput Phenotypic Screening Using iPSC-Derived Human Motor Neurons

At BrainXell, we established new technologies to rapidly differentiate ALS patient induced pluripotent stem cells (iPSCs) into large quantities of neurons.
TMT Quantification for Shotgun Proteomics: TIMS-QTOF Powered by PASEF content piece image
Poster

TMT Quantification for Shotgun Proteomics: TIMS-QTOF Powered by PASEF

Download this free poster to learn how a unique dual trapped ion mobility spectrometer (TIMS) coupled to a QTOF (timsTOF Pro) can be used for the analysis of isobaric labeling experiments.
PASEF Enhances the Speed, Sensitivity and Selectivity of Label-free Quantification content piece image
Poster

PASEF Enhances the Speed, Sensitivity and Selectivity of Label-free Quantification

Download this poster to learn how an adapted version of PEAKS™ enables identifications and label-free quantification from PASEF runs and enhances the speed, sensitivity and selectivity of label-free quantification.
Choosing the Right Parameters for Your UV-Vis Measurement content piece image
Poster

Choosing the Right Parameters for Your UV-Vis Measurement

The Agilent Optimum Parameters Poster is a handy wall chart that provides information about choosing solvents, cuvette types, and managing your instrument parameters.
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