Latest App Notes & Case Studies

Label-Free Single Cell Proteomics Workflow With the CellenONE Platform and the TimsTOF SCP

During pharmaceutical development and manufacturing, there is always the question: are you following methods for current good laboratory practice or current good manufacturing practice?

Targeted next-generation sequencing (NGS) is a well-established and powerful tool for somatic oncology research. NGS pipelines for the analysis of somatic variants require efficient methods for enriched library preparation from challenging sample types, relevant, optimized enrichment panels and advanced bioinformatic tools.

Download this app note to discover how you can overcome challenges such as maintaining the shape and size of spheroids to reduce variability.

Download this app note to discover a microplate reader that covers a broad range of cell viability assay readouts, provides high sensitivity and full flexibility and offers a fast and easy assay setup.

Discovery of novel immunotherapies that specifically target and enhance the T cell response against cancer is a rapidly expanding research area. Robust and relevant in vitro models for evaluation of these immunotherapies is essential throughout their development.

The University of Szeged is one of Hungary’s leading research institutions with a long history of pioneering scientific achievements. For generations, the university’s scholars have been focused on collecting and storing biological samples for educational purposes as well as for clinical, biomedical and physiological research.

In order to develop novel therapeutic treatments, it is key to understand the tissue-specific steroids metabolic pathways. Mass Spectrometry Imaging (MSI) is a powerful tool to visualize the distribution of such molecules involved in tissue metabolism.

Download this app note to discover methylation capture panels that show excellent performance across a wide range of methylation targets, enable highly optimized designs out of the box and are compatible with enzymatic or bisulfite conversion.

Download this app note to discover a solution that can be used with any biotinylated affinity molecule, enables floatation-based separation of diverse targets as well as provides workflows that are exceptionally gentle on delicate analytes.