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HIV Smuggles Its Genetic Material Into the Cell Nucleus
Research teams have now discovered that the HIV capsid has evolved into a molecular transporter. As such, it can directly breach a crucial barrier, which normally protects the cell nucleus against viral invaders.
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Syphilis-Like Diseases Were Already Widespread in America Before the Arrival of Columbus
Researchers discovered the genetic material of the pathogen Treponema pallidum in the bones of people who died in Brazil 2,000 years ago. This is the oldest verified discovery of this pathogen thus far.
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Protein TDP-43 Protects Us From Genetic Zombies
A new Cell Reports paper from Bing Yao’s lab in Emory’s Department of Human Genetics provides insights into mechanisms underlying several neurodegenerative diseases, such as ALS (amyotrophic lateral sclerosis) and Alzheimer’s.
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World's Largest Database of Weeds Is Open for Research
A new database of weeds can help scientists understand how traditional agricultural systems were managed throughout history and how global trends like the climate crisis could affect the resilience of our modern day food systems.
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Hepatitis Virus Mutations Challenge Drug Treatments
Researchers have closely monitored the evolution of the virus in two chronic patients undergoing combination therapy with the antiviral agent ribavirin and sofosbuvir, which was developed to combat hepatitis C.
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RNA Tagging Maps Gene Expression Changes During Ovulation
RNA tagging has revealed a slew of previously unknown molecular and cellular changes that drive ovulation, which could prove pivotal for developing therapeutics for infertility.
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Black Death Did Not Lead to Genetic Shift in Cambridgeshire
Researchers from the University of Cambridge investigated whether the Black Death led to a genetic shift in disease susceptibility in the surviving populations.
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DNA Methylation Important for Craniofacial Development
Cleft lip and palate are the most common craniofacial birth defects in humans. Yet despite decades of research, it’s still not known what causes most cases or what can be done to prevent them.
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Six Novel Urine Biomarkers Discovered for Active Renal Lupus
Six proteins found in urine have been identified as biomarkers for lupus nephritis, which may help the early identification of renal involvement in lupus.
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HIV Drugs May Prevent Complications From Bacterial Infections
Antiviral drugs used to fight HIV were shown to prevent these dangerous complications of infection. Insights into the mechanisms that lead to abscess formation open the door for new lines of thought about treating bacterial infections.
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