Latest App Notes & Case Studies

Identifying a respiratory viral infection can be challenging with different families of viruses being indistinguishable during the acute phase of illness, despite the outcome and long-term prognosis of the infection being different. The ability to diagnose a respiratory virus at the initial stage of infection can result in more effective treatment for the patient.

Download this app note to discover a method that facilitates optimal and reproducible conditions and thus reliable results, provides optimal activity-based cytokine dosing plus saves reagent.

One approach to develop drugs for infectious diseases involves a comprehensive understanding of human-pathogen protein interactions, as targeting host proteins helps reduce the possibility of drug resistance by creating a more significant evolutionary barrier for the virus.

Using genome-wide CRISPR knockout screens, followed by focused CRISPR screens, researchers at Boehringer Ingelheim probed the gene-phenotype relationship of human monocyte phagocytosis when the cells were challenged with Staphylococcus aureus.

The threat that emerging viruses pose to human health should not be underestimated. These viruses have acquired the ability to infect humans either due to interspecies transmission or naturally occurring changes in the viral genome.

PBMCs are routinely isolated and frozen down for experimental use, but what impact does cryopreservation have on these cells?

Expansion of Specific Lymphocyte Populations With 4Cell® Nutri-T Xeno-Free, Serum-Free Medium

The success of CAR T-cell therapy requires efficient expansion of specific subpopulations of patient-derived immune cells.

There are currently more than 140 monoclonal antibodies (mAbs) approved by the FDA as biotherapeutic agents, representing the most rapidly growing class of new drugs.

Hybridization capture-based target enrichment employs probes to select sequences of interest in a next generation sequencing (NGS) library.

Despite daily use in every life science laboratory, best pipetting practices are not as well-known as one might expect. Many users are self-taught and have never received formal pipetting training during their professional career.