Latest How To Guides

Sample management in the laboratory can be complicated, procedures vary significantly depending on the identity of the samples. This free guide describes key considerations for sample handling and management.

When Single Molecule, Real-Time (SMRT) sequencing was first released, it promised a huge shift in our approach to sequencing – moving away from methods that had up to that point been validated and entrenched in labs across the world. In this guide, PacBio's Nick Sisneros provides some insight into SMRT Sequencing and the tips and tricks that will ensure success in the template prep and sample preparation for use on this sequencing platform.

For most laboratory workflows, you’re only as good as your starting material. This is particularly true for next-generation sequencing (NGS). Here are several tips and tricks to preparing NGS libraries that hold true across all applications.

Download this guide to explore the essential guidelines that every laboratory and scientist should adhere to when handling sensitive or delicate samples.

This guide outlines protocols for the differentiation of hPSCs to either cortical neurons or hypothalamic neurons, provides key pointers for researchers who are undertaking these protocols for the first time.

Field spectroscopy enables scientists to measure how different materials interact with electromagnetic energy and therefore underpins the technology enabling us to view the world from the air or space. Here we explore some tips for perfecting your field spectroscopy skills.

This guide covers 4 aspects of cryopreservation to consider when preserving your precious samples.

Download this guide to discover:
- How to set up you HPLC for successful results
- How to troubleshoot common HPLC-related issues
- A step-by-step guide to using your HPLC and gaining meaningful data

Gaining ISO accreditation is any lab is a huge undertaking. This guide breaks down and outlines 9 practical steps you can take to help you prepare for the accreditation process.

The CRISPR interference (CRISPRi) machinery is an efficient, reversible and specific genome regulating platform for transcription control, without altering the target DNA sequence. This guide includes key steps on implementing CRISPRi using dCas9 derived from Streptococcus pyogenes.