Latest App Notes & Case Studies

This application note outlines how microalgal metabolism can be harnessed to produce novel food dyes with an automated screening approach.

Need a routine analytical technique that can provide protein expression profiling and targeted drug imaging? MALDI Imaging is used to determine the spatial distribution of molecules in a tissue section, for more complete multiomic information.

Many targets implicated in diseases are refractory to knockdown by traditional therapeutics like antibodies and small molecules. They represent an exciting new modality, repurposing small molecule chemical tools to achieve selective degradation

Microbial whole-genome sequencing (WGS) can support taxanomic classification, functional characterization and identify anti-microbial resistance in diverse sample types. It can provide greater resolution and more quantitative insights compared to shotgun and 16S methods.

The 16S ribosomal RNA (16S rRNA) gene is present in most bacterial species. As it contains both highly conserved and variable regions, it can be used to identify and classify different taxonomic levels.

This application note demonstrates how Single Cell Immune Profiling and Barcode Enabled Antigen Mapping (BEAM) can be used to profile thousands of hPBMCs from a single donor.

Metabolism has emerged as a key driver of T-cell antitumor function. This means that modulating metabolic programs of T cells can be used as a strategy to improve the antitumor efficacy of adoptive T-cell therapies.

The multi-attribute method (MAM) is a powerful LC-MS method that overcomes this challenge by simultaneously monitoring and quantifying multiple PQAs in a single injection.

Find out how scientists determined which of five extraction methods was optimal for use in a long-read sequencing workflow by comparing the sample quality, sample size and sequencing results.

Download this tech note to learn how mass spectrometry has gained substantial popularity for therapeutic mAb monitoring in clinical laboratories due to its great versatility to detect both tryptic peptides and intact light and heavy chains quantitatively.