Latest Posters

Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage cancer by early detection and identification of residual disease and subtype. However, a standard blood draw yields an average of only 10 ng of cfDNA, of which DNA derived from the tumor is a small minority.

Affinity purification platforms such as Protein A or L are well-established in the manufacturing process of therapeutic monoclonal antibodies. However, with the development of engineered modalities such as bi-specific antibodies, fragments and Fc-fusion proteins, challenges in the downstream process of these molecules arise.

Designing and performing assays that accurately measure small molecule binding kinetics is an important part of the drug discovery process. It allows researchers to predict the efficacy of potential novel therapeutics and make quick decisions about weak binders.

This poster compilation outlines the latest LC-MS/MS and QTOF MS methods for accurate environmental monitoring.

This poster demonstrates how a novel, precise and highly controlled iPSC reprogramming technology overcomes these limitations and enables the generation of mature cell types and isogenic models of neurodegenerative disease.

Many promising drugs which show efficacy in animal models have failed in the clinic due to interspecies variance in nociception mechanisms. Hence, consistent, scalable human in vitro models are required to accelerate potential therapeutics to the clinic.

While animal models and primary cells remain valuable resources, neuronal drug development faces many challenges. Not least, the variability and inaccuracy of traditional model systems can result in the failure to translate data into successful clinical trials.

Increased demand has led to an overwhelming volume of LC-MS/MS data and a requirement for analytical software that can simplify its interpretation. This poster highlights a new, comprehensive software solution capable of eliminating the otherwise overwhelming efforts of manual data interpretation.

Microglia play key roles in neurogenesis, synaptic remodeling, and are the first responders to infection in the brain. Hence, disease-relevant cell models are key to the success of neuroimmune and neurodegeneration research.

Formaldehyde fixed & paraffin-embedded (FFPE) tissue blocks are one of the most commonly used and archived sample types. However, some preservation approaches can result in the degradation of RNA and hinder transcriptome profiling .